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Pharmachem Research & Development Laboratories

Fumaric Acid

Fumaric Acid

Product Details

Chemical names trans-Butenedioic acid, trans-1,2-Ethylene-dicarboxylic acid
C.A.S. number 110-17-8
Chemical formula C4H4O4
Formula weight 116.07
Structural formula   
Assay Not less than 99.0% calculated on the dried basis
DESCRIPTION Odourless, white crystalline powder or granules
FUNCTIONAL USES Acidity regulator, flavouring agent (see "Table of specifications of flavouring agents")
Solubility (FNP 5) Soluble in ethanol; slightly soluble in water and in diethyl ether
pH (FNP 5) 2.0 - 2.5 (1 in 30 solution)

Fumaric acid is a valuable compound used in foods, beverages, detergents, animal feed, pharmaceuticals and miscellaneous industrial products. It is produced on a large scale by the petrochemical route but the current tendency is towards implementing “green production” and environmental friendly technologies like biotechnological production of fumaric acid using low-cost raw materials. In this context, numerous studies focus on improving the fermentation process not only by using renewable raw material and genetically modified microorganisms, but also by developing and applying different downstream techniques for easy recovery of fumaric acid from the fermented broth. This review presents the main methods for production and separation of fumaric acid, highlighting the advantages and disadvantages of these and the potential economic impact in industry.


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